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Preparation API
Ticagrelor Tablets
2023-08-14

【Drug Name】
Generic Name: Ticagrelor Tablets
English name: Ticagrelor Tablets
Hanyu Pinyin: Tigeruiluo Pian

Ingredients
The active ingredient of this product is Ticagrelor, whose chemical name is: (1S, 2S, 3R, 5S)-3-[7-{[(1R, 2S)-2-(3, 4-difluorophenyl)cyclopropyl]amino}

-5-propanethio-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-(2-hydroxyethoxy)cyclopentane-1,1,2-triazole-3-yl). hydroxyethoxy)cyclopentane-1,2-diol

【Properties】
   This product is yellow film-coated tablets, white or off-white after removing the coating.

Indications
This product is used in combination with aspirin to reduce the incidence of cardiovascular death, myocardial infarction, and stroke in patients with acute coronary syndrome (ACS) or in patients with a history of myocardial infarction associated with at least one risk factor for atherosclerotic thrombotic events (see Clinical Trial PEGASUS Study).
It is superior to clopidogrel for at least the first 12 months after the onset of ACS.
The combination of this product with aspirin was studied in patients with ACS. It was found that aspirin maintenance doses greater than 100 mg reduced the clinical efficacy of Tegretol in reducing composite endpoint events; therefore, aspirin maintenance doses should not exceed 100 mg daily.

【Specifications】
90mg/tablet